Weight Loss, The Anti-Aging Way

**A.FreeRadical** · 08-31-2005, 11:47 AM

WEIGHT LOSS, THE ANTI-AGING WAY
by the American Academy of Anti-Aging Medicine

This is the conclusion. Read the entire article at:
http://www.worldhealth.net/p/286,2059.html

THE ANTI-INSULIN PROGRAM

1) Seriously reduce (better yet, eliminate) from the diet all processed, refined, junk food, high sugar (sucrose, fructose, glucose), high white flour "foods": bread, pasts, cake, pie, candy, ice cream, crackers, cereal, corn/potato chips, snack bars, waffles/pancakes, soft drinks, doughnuts, sweet syrups, ad infinitum.
2) Minimize intake of salt, especially salty CHO-foods: pretzels, chips, crackers, etc. "Salt increases plasma glucose and insulin response to starchy foods." (4)
3) Increase glucagon - stimulating with lean protein: low-fat (ideally range-fed, organic) beef, lamb, chicken. turkey, fish etc.
4) Reduce CHO-intake from the typical American/British levels of 250-400 grams/day to 75-150 grams/day. These carbohydrates should be mainly vegetables, with small amounts of brown rice, millet, beans, almonds, pumpkin seeds and other unrefined, high-fibre natural foods.
5) Take 40-60 minute brisk walks, 4-6 days/week. Avoid walking in highly polluted areas and/or times of day, as toxins from auto exhaust may inhibit mitochondrial burning of fuel (i.e. fat) for energy.
6) Take various supplements discussed in this article - e.g. C, B6, B3, Zinc, Magnesium, GLA, EPA, etc.

ADDITIONAL NUTRITIONAL/PHARMACOLOGIC AIDS TO FAT LOSS/INSULIN REDUCTION

1) Chromium Picolinate. This form of chromium is well absorbed, and has been shown in various animal and human studies to aid in fat loss while at least modestly enhancing lean body mass. (16) "The ability of chromium picolinate to enhance insulin responsiveness has been demonstrated in rat myoblast cell cultures. 72-h pre-incubation with chromium picolinate (50ng Cr/ml) resulted in a 60% increase in insulin binding, and markedly enhanced glucose and leucine uptake...." (16) Dosage: 200mcg Chromium (as picolinate) two or three times daily for women; 200mcg three times daily or 400mcg twice daily for men.
2) Obesity, aging, chronic dieting, genetics, lack of exercise and lack of cold exposure may all lead to "subclinical" hypothyroidism, often involving deficient conversion of less active T4 to T3. T3 decreases the activity of D5D, reducing pro-insulin PGE2, just as do glucagon and EPA. (7) T3 also stimulates fat burning. (4) Ideally one should use T3 (Cytomel) only under a physician's care and guidance, but those who fit the low-thyroid profile and suffer from chronic obesity and fatigue, and who are willing to take practical, moral and legal responsibility for their own actions, may wish to experiment with modest doses of T3 - i.e., 2-3 mcg once or twice daily, taken morning and/or early afternoon. T3 is fast/short-acting, and most effects will be gone within 24 hours or less. Nonetheless, there is some risk here - caveat emptor! Heart palpitations, excessive sweating, racing thoughts, headaches, irritability, and insomnia are all hints - it's not for you! Those with known or suspected (past or present) hyperthyroidism, even if obese, should not use T3 without a doctor's care. Similarly those with any other serious disease states - especially heart arrhythmia's/heart disease - should be extremely cautious in T3 use.
3) Anti-cortisol states. Since cortisol levels tend to increase with age (and stress), and since cortisol promotes both obesity and insulin resistance, this is a key strategy to normalize weight/insulin levels. DHEA, (7) and high dose vitamin C (17) may all help lower elevated cortisol levels. DHEA: 10-50mg A.M. Gerovital-H3: 100mg A.M. Dilantin (Phenytoin) 25-50mg at bedtime. Vitamin C: 500-1000mg 3-4 times daily.
4) L-Tryptophan/5-Hydroxytryptophan (Oxitriptan). Several human studies with 5HTP, the precursor of serotonin, have found good weight loss results with 5HTP. (18,19) There is evidence that some humans compulsively snack on CHO foods to feel better. The large insulin releases generated by such "carbo-bingeing" preferentially increase tryptophan/serotonin in the brain, temporarily reducing anxiety and depression in such people. (20) By providing an alternative, non-insulin-driven way to increase brain serotonin, L-Tryptophan, supplements may help reduce weight not only by reducing total caloric intake, but especially by reducing CHO intake, thus lessening hyper-insulinemia/insulin resistance. In the 1992 Italian study (19), 300mg/5HTP supplements may help reduce weight not only by reducing total caloric intake, but especially by reducing CHO intake, thus lessening hyperinsulinemia/insulin resistance. In the 1992 Italian study, (19) 300mg 5HTP 3 times daily before meals reduced women's caloric intake over a twelve week period from 3232 cal/day to 1273 cal/day, while reducing CHO intake from 350gm/day to 150gm/day. Weight dropped an average of eleven pounds. (The study did use special enteric-coated 5HTP capsules to prevent gut irritation) Ed [IAS provides same Italian 5HTP]. Taking 1000-1500mg L-Tryptophan at bedtime, or 50-100mg 5HTP before meals may reduce CHO-craving and intake.
5) Pro-GH supplements. As noted earlier, PGE1 may enhance GH release. so all the PGE1-enhancing nutrients (GLA, EPA, B3, B6, C, zinc, magnesium) may be helpful here. Hydergine has been shown to increase GH-release in the elderly with long-term usage at 1.5mg every 6 hours. (21) The authors of this study also note that bromocryptine (Parlodel) may also enhance adult GH-release. They also note that the enhanced pituitary GH-release from hydergine seems to be related to an increase in brain (hypothalamic) dopamine status, which normally declines (often precipitously) with age. Thus the dopamine-enhancing agent Deprenyl may also be useful as part of a GH-restoration program.
6) Mitochondrial energizers and protectants. In a healthy human, storage fat is at a minimum and sooner or later all fat-dietary, body-manufactured, and storage fat - ends up as "fuel for the furnace" - i.e. the trillions of mitochondrial "power plants " found in most of our cells. Vitamins B1, B2, B3, B5 (pantothenic acid), and biotin, as well as NADH, alpha-lipoic acid, CoQ10/Idebenone, magnesium and manganese are all necessary "spark plugs" to facilitate burning fat and sugar for energy. 10-100mg B1, B2, B3, 50-200mg B5, 1-10mg biotin, 5-20mg NADH, 50-300mg alpha-lipoic acid, 60-300mg CoQ10 and/or 45-135mg Idebenone, 200-500mg magnesium, and 3-10mg managanese may optimize mitochondrial energy cycles. Since the mitochondrial structures inevitably generate massive amounts of free radicals in turning fuel into energy, and since these structures are rich in easily rancidified polyunsaturated fatty acids, a panoply of antioxidants - e.g. 100-400 IU vitamin E, 500-2000mg vitamin C, 100-200mcg selenium, 50-300mg alpha-lipoic acid, 500-1000mg N-acetylcysteine, 2mg copper as copper sebacate (SOD-mimetic), 50-100mg grape seed extract/pycnogenol, 300-500mg silymarin - may help protect the essential "fat burning furnaces." In addition, 1gm L-carnitine twice daily on an empty stomach may facilitate fat burning - carnitine is the "shuttle molecule" that "escorts" fatty acids into mitochondria where they are then oxidized. (22) ALC (acetyl-L-carnitine) may also be a useful mitochondrial regenerator - mitochondria become progressively deformed and dysfunctional with aging. Dosage: 1-3gms/day. Ward Dean suggests this dose can be half L-carnitine and half ALC to achieve successful mitochondrial regeneration. (23)
7) Caffeine. Caffeine, whether from coffee or as a "drug", has many benefits for aiding fat loss. However, excessive doses (probably 300mg/day and up, on average) may pose risks of "caffeinism", with such symptoms as headaches, restlessness, irritability, insomnia, anxiety, excessive urination, gut irritation, heart palpitations, and muscle tremors. (15) A thermogenic/fat burning dose is probably 100-200mg daily - i.e. the equivalent of one to two cups of coffee/day, or two to four cups made with half decaf and half regular. Caffeine taken with a meal may induce increased thermogenesis - burning fat to make heat. (15) It may increase resting metabolic rate - our resting metabolism burns 60-70% of our total daily energy consumption. (15) Caffeine preadministration 45-60 minutes before exercise has been shown to spare liver/muscle glycogen and to enhance fatty acid burning in humans. (24) Caffeine taken after at least an eight hour fast, i.e. in the morning after arising, may be especially effective when combined with a 40-60 minute brisk walk, to enhance burning of stored body fat. (24)

**dbflgirl** · 08-31-2005, 11:13 PM

This is great information, AFR. Thanks for sharing.

**skelooth** · 09-01-2005, 01:22 PM

and I know it works because AFR has been consistently getting younger

**A.FreeRadical** · 09-02-2005, 09:49 PM

Quote:

Originally Posted by skelooth

and I know it works because AFR has been consistently getting younger

This is true physiologically. I haven't figured out how to do that chonologically, yet... But... wait... I have this DeLorean and plans for a flux inverter...

*

Eileen · 09-04-2005, 06:05 PM

Excellent info. I'm going to print it out and keep it with my clippings.

08-31-2005, 11:47 AM	#1
A.FreeRadical the Epicurean Bodybuilder Join Date: Aug 2005 Posts: 2,245 Recipes: 0 Rep Power: 58	Weight Loss, The Anti-Aging Way WEIGHT LOSS, THE ANTI-AGING WAY by the American Academy of Anti-Aging Medicine This is the conclusion. Read the entire article at: http://www.worldhealth.net/p/286,2059.html THE ANTI-INSULIN PROGRAM 1) Seriously reduce (better yet, eliminate) from the diet all processed, refined, junk food, high sugar (sucrose, fructose, glucose), high white flour "foods": bread, pasts, cake, pie, candy, ice cream, crackers, cereal, corn/potato chips, snack bars, waffles/pancakes, soft drinks, doughnuts, sweet syrups, ad infinitum. 2) Minimize intake of salt, especially salty CHO-foods: pretzels, chips, crackers, etc. "Salt increases plasma glucose and insulin response to starchy foods." (4) 3) Increase glucagon - stimulating with lean protein: low-fat (ideally range-fed, organic) beef, lamb, chicken. turkey, fish etc. 4) Reduce CHO-intake from the typical American/British levels of 250-400 grams/day to 75-150 grams/day. These carbohydrates should be mainly vegetables, with small amounts of brown rice, millet, beans, almonds, pumpkin seeds and other unrefined, high-fibre natural foods. 5) Take 40-60 minute brisk walks, 4-6 days/week. Avoid walking in highly polluted areas and/or times of day, as toxins from auto exhaust may inhibit mitochondrial burning of fuel (i.e. fat) for energy. 6) Take various supplements discussed in this article - e.g. C, B6, B3, Zinc, Magnesium, GLA, EPA, etc. ADDITIONAL NUTRITIONAL/PHARMACOLOGIC AIDS TO FAT LOSS/INSULIN REDUCTION 1) Chromium Picolinate. This form of chromium is well absorbed, and has been shown in various animal and human studies to aid in fat loss while at least modestly enhancing lean body mass. (16) "The ability of chromium picolinate to enhance insulin responsiveness has been demonstrated in rat myoblast cell cultures. 72-h pre-incubation with chromium picolinate (50ng Cr/ml) resulted in a 60% increase in insulin binding, and markedly enhanced glucose and leucine uptake...." (16) Dosage: 200mcg Chromium (as picolinate) two or three times daily for women; 200mcg three times daily or 400mcg twice daily for men. 2) Obesity, aging, chronic dieting, genetics, lack of exercise and lack of cold exposure may all lead to "subclinical" hypothyroidism, often involving deficient conversion of less active T4 to T3. T3 decreases the activity of D5D, reducing pro-insulin PGE2, just as do glucagon and EPA. (7) T3 also stimulates fat burning. (4) Ideally one should use T3 (Cytomel) only under a physician's care and guidance, but those who fit the low-thyroid profile and suffer from chronic obesity and fatigue, and who are willing to take practical, moral and legal responsibility for their own actions, may wish to experiment with modest doses of T3 - i.e., 2-3 mcg once or twice daily, taken morning and/or early afternoon. T3 is fast/short-acting, and most effects will be gone within 24 hours or less. Nonetheless, there is some risk here - caveat emptor! Heart palpitations, excessive sweating, racing thoughts, headaches, irritability, and insomnia are all hints - it's not for you! Those with known or suspected (past or present) hyperthyroidism, even if obese, should not use T3 without a doctor's care. Similarly those with any other serious disease states - especially heart arrhythmia's/heart disease - should be extremely cautious in T3 use. 3) Anti-cortisol states. Since cortisol levels tend to increase with age (and stress), and since cortisol promotes both obesity and insulin resistance, this is a key strategy to normalize weight/insulin levels. DHEA, (7) and high dose vitamin C (17) may all help lower elevated cortisol levels. DHEA: 10-50mg A.M. Gerovital-H3: 100mg A.M. Dilantin (Phenytoin) 25-50mg at bedtime. Vitamin C: 500-1000mg 3-4 times daily. 4) L-Tryptophan/5-Hydroxytryptophan (Oxitriptan). Several human studies with 5HTP, the precursor of serotonin, have found good weight loss results with 5HTP. (18,19) There is evidence that some humans compulsively snack on CHO foods to feel better. The large insulin releases generated by such "carbo-bingeing" preferentially increase tryptophan/serotonin in the brain, temporarily reducing anxiety and depression in such people. (20) By providing an alternative, non-insulin-driven way to increase brain serotonin, L-Tryptophan, supplements may help reduce weight not only by reducing total caloric intake, but especially by reducing CHO intake, thus lessening hyper-insulinemia/insulin resistance. In the 1992 Italian study (19), 300mg/5HTP supplements may help reduce weight not only by reducing total caloric intake, but especially by reducing CHO intake, thus lessening hyperinsulinemia/insulin resistance. In the 1992 Italian study, (19) 300mg 5HTP 3 times daily before meals reduced women's caloric intake over a twelve week period from 3232 cal/day to 1273 cal/day, while reducing CHO intake from 350gm/day to 150gm/day. Weight dropped an average of eleven pounds. (The study did use special enteric-coated 5HTP capsules to prevent gut irritation) Ed [IAS provides same Italian 5HTP]. Taking 1000-1500mg L-Tryptophan at bedtime, or 50-100mg 5HTP before meals may reduce CHO-craving and intake. 5) Pro-GH supplements. As noted earlier, PGE1 may enhance GH release. so all the PGE1-enhancing nutrients (GLA, EPA, B3, B6, C, zinc, magnesium) may be helpful here. Hydergine has been shown to increase GH-release in the elderly with long-term usage at 1.5mg every 6 hours. (21) The authors of this study also note that bromocryptine (Parlodel) may also enhance adult GH-release. They also note that the enhanced pituitary GH-release from hydergine seems to be related to an increase in brain (hypothalamic) dopamine status, which normally declines (often precipitously) with age. Thus the dopamine-enhancing agent Deprenyl may also be useful as part of a GH-restoration program. 6) Mitochondrial energizers and protectants. In a healthy human, storage fat is at a minimum and sooner or later all fat-dietary, body-manufactured, and storage fat - ends up as "fuel for the furnace" - i.e. the trillions of mitochondrial "power plants " found in most of our cells. Vitamins B1, B2, B3, B5 (pantothenic acid), and biotin, as well as NADH, alpha-lipoic acid, CoQ10/Idebenone, magnesium and manganese are all necessary "spark plugs" to facilitate burning fat and sugar for energy. 10-100mg B1, B2, B3, 50-200mg B5, 1-10mg biotin, 5-20mg NADH, 50-300mg alpha-lipoic acid, 60-300mg CoQ10 and/or 45-135mg Idebenone, 200-500mg magnesium, and 3-10mg managanese may optimize mitochondrial energy cycles. Since the mitochondrial structures inevitably generate massive amounts of free radicals in turning fuel into energy, and since these structures are rich in easily rancidified polyunsaturated fatty acids, a panoply of antioxidants - e.g. 100-400 IU vitamin E, 500-2000mg vitamin C, 100-200mcg selenium, 50-300mg alpha-lipoic acid, 500-1000mg N-acetylcysteine, 2mg copper as copper sebacate (SOD-mimetic), 50-100mg grape seed extract/pycnogenol, 300-500mg silymarin - may help protect the essential "fat burning furnaces." In addition, 1gm L-carnitine twice daily on an empty stomach may facilitate fat burning - carnitine is the "shuttle molecule" that "escorts" fatty acids into mitochondria where they are then oxidized. (22) ALC (acetyl-L-carnitine) may also be a useful mitochondrial regenerator - mitochondria become progressively deformed and dysfunctional with aging. Dosage: 1-3gms/day. Ward Dean suggests this dose can be half L-carnitine and half ALC to achieve successful mitochondrial regeneration. (23) 7) Caffeine. Caffeine, whether from coffee or as a "drug", has many benefits for aiding fat loss. However, excessive doses (probably 300mg/day and up, on average) may pose risks of "caffeinism", with such symptoms as headaches, restlessness, irritability, insomnia, anxiety, excessive urination, gut irritation, heart palpitations, and muscle tremors. (15) A thermogenic/fat burning dose is probably 100-200mg daily - i.e. the equivalent of one to two cups of coffee/day, or two to four cups made with half decaf and half regular. Caffeine taken with a meal may induce increased thermogenesis - burning fat to make heat. (15) It may increase resting metabolic rate - our resting metabolism burns 60-70% of our total daily energy consumption. (15) Caffeine preadministration 45-60 minutes before exercise has been shown to spare liver/muscle glycogen and to enhance fatty acid burning in humans. (24) Caffeine taken after at least an eight hour fast, i.e. in the morning after arising, may be especially effective when combined with a 40-60 minute brisk walk, to enhance burning of stored body fat. (24) __________________ "Is it going to be the red pill or the blue pill, Neo? The red pill will answer the question 'What is the Matrix?' Choose carefully. Remember, all I'm offering is the truth. Nothing more." Ron Paul for President, 2008 A.FreeRadical ...the Epicurean bodybuilder Height: 5'9", Age: 62, My last high on 2/1/2006 was 196 lbs. My last low on 8/08/2006 was 167.5 lbs. Cutting until I am lean Starting weight: 190 lbs. bodyfat: 19.7% November 27th: 183 lbs. bodyfat: 18.3% bodyfat Goal Weight: 176 lbs with no more than 10% bodyfat My recipe collection

09-01-2005, 01:22 PM	#3
skelooth eh heh heh Join Date: Aug 2005 Location: Behind you Posts: 7,203 Recipes: 0 Rep Power: 158	and I know it works because AFR has been consistently getting younger __________________ http://loseover100lbs.com/misc-f7.html

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08-31-2005, 11:13 PM	#2
dbflgirl Silver Member Join Date: Aug 2005 Location: Hurricane Alley Posts: 646 Recipes: 0 Rep Power: 19	This is great information, AFR. Thanks for sharing.

09-04-2005, 06:05 PM	#5
Eileen New Member Join Date: Jul 2005 Posts: 12 Recipes: 0 Rep Power: 0	Excellent info. I'm going to print it out and keep it with my clippings.