MCWtrainer

I cannot take credit for this product, Pu mentioned it to me and asked if I would post it. So for those of you who like this supplement, thank Pu for it. I am simply the person giving you the information. Here is a link to their site, basically all the information posted here is from there and some other sources...

http://www.bioperine.com/index.html

Bioperine® is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent of piperine. Bioperine® may be co-administered with various nutrients for both human and animal health.

Black pepper is a common household spice. Extract from black pepper has also been used extensively as a medicine by our ancestors especially in India .

Bioperine® is an extract obtained from the black pepper fruit that is cultivated in the damp, nutrient-rich soil regions of southern India . The delicate pepper berries are harvested just prior to ripening and then sun dried to assure optimum maturity and quality. The extract of piperine, called Bioperine® in the patented form, has been clinically tested in the United States . Bioperine® significantly enhances the bioavailability of various supplement nutrients through increased absorption.


How does Bioperine® work?
The metabolic process that generates energy at the cellular level in the human body is called thermogenesis. Though thermogenesis has been identified as a key factor in maintaining weight loss, it has also been identified as playing an integral role in utilizing the daily food and nutrients that the human body consume s. It sets in motion the mechanisms that lead to digestion and subsequent gastrointestinal absorption. Piperine, in the patented form of Bioperine®enhances the body's natural thermogenic activity - hence the term Thermonutrient®.

This enhancement may be explained as a means of increasing the thermal energy sufficient to "power up" the mechanism related to thermogenesis. This in turn results in increased metabolic processes that creates a "demand" for "supply" of a broad range of nutrients that contribute to metabolism, i.e. vitamins, minerals, herbals, amino acids, etc. It is as if Bioperine® activates a metabolic paddle wheel, of sorts, that selectively provides a more efficient mode of nutrient transportation into the blood.


The Advantages of Bioperin®
Bioperine® is the only product sourced out of piperine to obtain a patented status for its ability to increase the bioavailability of nutritional compounds. Secondly, it is the only source from piperine to have undergone clinical studies in the U.S. to substantiate its safety and efficacy for nutritional use.

The nutritional materials which may be co-administered with Bioperine® are the following groups :
Herbal extracts :
(e.g. CURCUMIN, BOSWELLIA SERRATA, ASHWAGANDHA, GINKGO BILOBA and CAPSAICIN)

Water-soluble vitamins :
(e.g. Vitamin B1, Vitamin B2, Niacinamide, Vitamin B6, Vitamin B12, Folic acid and Vitamin C)

Fat-soluble vitamins :
(e.g. Vitamin A, Vitamin D, Vitamin E, and Vitamin K)

Antioxidants :
(e.g. Vitamin A, Vitamin C, Vitamin E, alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein/zeaxanthin, pine bark bioflavonoids complex, germanium, selenium and zinc).

Amino acids :
(e.g. lysine, isoleucine, leucine, threonine, valine, tryptophan, phenylalanine, and methionine)

Minerals :
(e.g calcium, iron, zinc, vanadium, selenium, chromium, iodine, potassium, manganese, copper and magnesium).


Here is a link to their clinical studies...
http://www.bioperine.com/clinical_studies.htm

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Nonspecific mechanisms promoting rapid absorption of nutrients

a. Increases blood supply to the GI tract

b. Increases emulsifying content of the gut

c. Increases active nutrient transport



Here is a Peer Review...
http://www.bioperine.com/reviewed_articles.htm

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It's in your fat burner...
http://www.diet-supplement-review.com/bioperine.html

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What is it?
Bioperine® is a standardized piperine extract obtained from the fruits of the black pepper and/or long pepper plants. It has little effect on weight loss, lean muscle gain or sporting performance. Rather, the main effect of Bioperine® is to enhance the bioavailability of various nutrients consumed with it [1].


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Who should use it?
Bioperine® is suitable for anyone who wants to increase the bioavailability and absorption of the supplements they use.


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How does it work?
The sensation of warmth in the mouth after consuming black pepper is primarily due to the presence of the alkaloid piperine, which was isolated at the beginning of the 19th century by the German scientist Derstad. Bioperine® is a standardized piperine extract obtained from the fruits of the black pepper and/or long pepper plants that are cultivated in the damp, nutrient-rich soil regions of south India. The delicate pepper berries are hand harvested prior to ripening and then sun dried.

Bioperine® has been clinically tested in the United States and shown to significantly enhance the bioavailability of supplemented nutrients through increased absorption [2]. Studies show that Bioperine® increases the absorption of coenzyme Q10 by approximately 30% [1], with some trials demonstrating a 20-fold increase in bioavailability [3]. Bioperine® also has several U.S. patents as a bioavailability enhancer (including # 5,536,506, # 5,744,161 and # 5,972,382). The only clinical studies done with piperine for nutritional purposes are with Bioperine®.


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How should I use it?
Approximately 2-5 milligrams of Bioperine® is needed to enhance the bioavailability and absorption of nutrients consumed with it. What results should I expect? Bioperine® will enhance the bioavailability of co-administered nutrients by 30% or more.


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What should I use it with?
Some of the nutrients which may be co-administered with Bioperine® include herbal extracts (such as Curcumin, Boswellia serrata, Ashwagandha, Ginkgo biloba and Capsaicin), water-soluble vitamins (such as Vitamin B1, Vitamin B2, Niacin, Vitamin B6, Vitamin B12, Folic acid and Vitamin C), fat-soluble vitamins (including Vitamin A, Vitamin D, Vitamin E, and Vitamin K), amino acids (lysine, isoleucine, leucine, threonine, valine, tryptophan, phenylalanine, and methionine) and various minerals (including calcium, iron, zinc, vanadium, selenium, chromium, iodine, potassium, manganese, copper and magnesium).

Research
1. Badmaev, V. V., Majeed, M., & Prakash, L. (2000). Piperine derived from black pepper increases the plasma levels of coenzyme q10 following oral supplementation. Journal of Nutritional Biochemistry, 11, 109-113
2. Velpandian, T., Jasuja, R., Bhardwaj, R.K., Jaiswal, J., & Gupta, S.K. (2001). Piperine in food: interference in the pharmacokinetics of phenytoin. European Journal of Drug Metabolism and Pharmacokinetics, 26, 241-247
3. Shoba, G., Joy, D., Joseph, T., Majeed, M., Rajendran, R., & Srinivas, P.S. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica, 64, 353-356 -



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